ABSTRACT
Background: Anthropometry measurements are very useful and have definite medico legal significance. In case of missing persons in the absence of pelvis and cranium, the remains of long bones of an individual play an important role in anthropological practice for morphometric analysis. The stature of an individual can be estimated from the humerus alone. Estimating the mean values of different segments of humerus helps in forensic and anthropometric practice. Previous studies have confirmed that humerus is one of the strongest long bones of the human skeleton and its fragments can be recorded in a forensic case. The present study was done to assess the mean values of different segments of humerus and their correlation with its length.Methods: Seventy dry adult humerus bones (32 rights and 38 left) were collected randomly from the anatomy department. Broken bones and the bones in a poor condition were excluded from the study. The segments of the humerus were studied for morphometric analysis.Results: All of the measurements were obtained in millimetres (mm). The measurement of the maximum length of humerus (MHH) was done by using an otseometric board and the different segments of humerus were measured by a vernier calliper (precision=0.cm). Mean and SD were calculated.Conclusions: This study has helped us to observe the maximum length of humerus and the mean values of the different segments of humerus in a sample of Indian population. The study also suggests that there are some differences between various segments of humerus within different populations.
ABSTRACT
Background: The present randomized controlled study was carried out over a period of one year to observe the effects of perioperative parenteral nutrition on wound healing and hospital stay. Methods: Hundred patients, admitted in Department of surgery, Government Medical Srinagar were divided into two groups of 50 each. Group A (Study group) and group B (Control group). Group A patients were given perioperative parenteral nutritional support whereas patients in control group received no perioperatve parenteral nutritional support. Results: Complications like wound infections, sepsis, abscess formation, anastomotic leak and wound dehiscence were considerably less in the study group. The time period to resolve complications and overall hospital stay was also less in the study group. Conclusions: Parenteral perioperative nutritional support has a definite role in the management of selected surgical patients. It reduces the septic or non-septic complication and over all post-operative hospital stay. It should be included in the management of surgical patients if affordable.
ABSTRACT
Background: Meissner’s corpuscle is the most complex sensory receptors of the skin; providing information about rapidly fluctuating mechanical forces acting on the hairless skin. Aim of current study was to study density and structural changes in human Meissner’s corpuscles at different ages Methods: Samples were obtained from finger tips of fifteen persons and divided into three groups according to age: group A <15years; group B: 16-45 years and group C: 46-72 years. 5 μm thick sections were prepared, impregnated with silver and observed under compound light microscope. Density of Meissner’s corpuscles (Mcs) was studied by calculating Meissner’s Index (MI). Results: In group A, the MI was 0.86-0.90, which increased to 0.96 in group B and dropped in group C to 0.4 (in the seventh decade). The analysis of variance showed significant difference (P = 0.019) in MIs of the three age groups. The size of the Mcs was largest in group B, followed by group C and smallest in group A. The analysis of variance showed that there was highly significant difference (P = 0.003) between the size of Mcs in all the three age groups. It was observed that morphology of Mcs alter with age. In children these consisted of rudimentary coil of nerve fibers around collection of cells. In adults the intra-corpuscular nerve fibers were compressed into a tight spiral and modifications of nerve fibers, like end bulbs, varicosities and networks, were well developed. In old age Mcs were attenuated consisting of tangled mass of nerve fibers. Conclusion: It can be concluded that in adults the Mcs are greater in number, larger in size and complicated in structure, compared to young and old people.
ABSTRACT
Background: Lithium is routinely used to treat mania and other psychiatric disorders. It prevents the mood swing changes in bipolar disorders and the treatment is usually prolonged. Aim of current study was to observe histological changes in the thyroid gland of lithium carbonate treated albino rats. Methods: Sixty albino rats were taken and divided into two groups, group A (control group) of 15 animals, were fed with normal diet and group B of 45 animals, were fed normal diet along with lithium carbonate at the dose of 30mg/kg body weight daily. The animals were sacrificed at four, eight and twelve week’s interval, 5μm sections prepared and stained with haematoxylin and eosin stain. Results: Microscopic changes in thyroid gland of albino rats were evident after 8 weeks of drug administration which include marked pleomorphism, shrinkage in size of thyroid follicles, excess of colloid and marked vacuolations in acini. At 12th week of study, follicles were found both macro and micro follicular, with variable lining epithelium and hyperchromatic nuclei. Lining epithelium of some follicles was disrupted. The stroma was infiltrated with lymphocytes and eosinophils and there were some interfollicular hemorrhages. Conclusions: Lithium given over prolonged period will cause macro and micro follicular goiter with hyperplastic epithelium and hyper chromatic nuclei, hyperplasia of stroma with increased vascularity, sometimes hemorrhages and finally may lead to thyroiditis like picture. So, it is advised that patients on lithium therapy should be periodically evaluated for thyroid dysfunction.
ABSTRACT
Dermatoglyphics is the study of finger print patterns and the term was coined by Harold Cummins in 1926. Finger prints are imprints of epidermal ridges, which are formed in early embryonic life, during 10th to 16th week of intrauterine life and remain permanent during whole life. Dermatoglyphic patterns have polygenic inheritance and are affected by environmental factors in the uterus. Finger print patterns are mainly of three types: arches whorls and loops; though there are more than 100 ridge characteristics, called Galton’s details, in a single rolled finger print. Dermatoglyphics is not only used in the identification of an individual but also serves as a mirror of one’s potential and talent. In this review, we will be discussing Dermatoglyphics and its important role in the diagnosis of chromosomal disorders and other diseases which have some genetic bases.
ABSTRACT
Background: Human glabrous skin has very rich nerve supply in the form of specialized nerve endings like Meissner’s corpuscles, Pacinian corpuscles, Krause end bulbs etc for carrying sensory information to brain. Aim of study: To study the structure, pattern of innervations and nerve terminations of human Meissner’s corpuscle. Methods: Skin samples from sixty human beings (age range 2 to 72 years) were taken, sections prepared and stained with a cytological (Haematoxylin – Eosin and Vongieson’s stains) and a neural stain (Silver Impregnation). Results: With cytological stain, Meissner’s corpuscles were seen in dermal papillae of glabrous skin, each consisting of a cellular structure having a peripheral capsule and central core of transversely arranged cells. With neural stain, each corpuscle was seen to be oval, globular or cylindrical structure, having a capsule surrounding the core of spirally arranged nerve fibers, sandwiched by Schwann cells. In between nerve fibers of the core were seen small bundles of collagen fibers. 2-6 nerve fibers innervated each Mc from the sub corial plexus of nerves and formed various patterns of nerve endings like networks, end bulbs and varicosities inside the Meissner’s corpuscle. Conclusion: Meissner’s corpuscle is a complex structure composed of capsule - consisting of spindle shaped capsular cells interspersed in collagen fibers, surrounding a core of helically arranged nerve fibers, Schwann cells and collagen fibers.